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Plecanatide, sold under the brand name Trulance, is a medication for the treatment of chronic idiopathic constipation (CIC) [4] and irritable bowel syndrome with constipation. [5] It is available in India under the brand name Plectide (OQM Div, MSN Laboratories, India).
Linaclotide, (sold under the brand name Linzess in the US and Mexico, and as Constella elsewhere) [6] is a drug used to treat irritable bowel syndrome with constipation and chronic constipation with no known cause.
The WHO Model List of Essential Medicines for Children (aka Essential Medicines List for Children [1] or EMLc [1]), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe in children up to twelve years of age to meet the most important needs in a health system.
The UL for children 1–3 years of age is 400 mg; 4–8 years of age is 650 mg; 9–11 years of age is 1200 mg. Parents should not give their child more than the recommended dose of Flintstones Plus Immunity Support because they can easily exceed their child's UL for vitamin C. This can lead to adverse effects, such as diarrhea and kidney stones.
Age appropriateness is considered essential for children's skills development. Children's motor, cognitive and social skills are formed through several development stages . Looking at a child's functional development involves observing whether or not the child has mastered certain developmental milestones and expectations for their age.
Formulations of delayed-release budesonide are an effective treatment for mild-to-moderately active Crohn's disease involving the ileum and/or ascending colon. [25] A Cochrane review found evidence for up to three months (but not longer) of maintenance of remission in Crohn's disease, concluding that budesonide is not effective for maintenance of remission in CD.