Ads
related to: when to take phosphatidylcholine and brain function development 1wiserlifestyles.com has been visited by 100K+ users in the past month
Search results
Results From The WOW.Com Content Network
L-α-Glycerophosphorylcholine (alpha-GPC, choline alfoscerate, sn-glycero-3-phosphocholine) is a natural choline compound found in the brain. It is also a parasympathomimetic acetylcholine precursor [ 1 ] which has been investigated for its potential for the treatment of Alzheimer's disease [ 2 ] and other dementias .
1-Oleoyl-2-palmitoyl-phosphatidylcholine. Phosphatidylcholines (PC) are a class of phospholipids that incorporate choline as a headgroup.They are a major component of biological membranes and can easily be obtained from a variety of readily available sources, such as egg yolk or soybeans, from which they are mechanically or chemically extracted using hexane.
These LPC analogues are metabolically stable, and several ALPs such as edelfosine, miltefosine and perifosine are under research and development as drugs against cancer and other diseases. [ 6 ] [ 7 ] Lysophosphatidylcholine processing has been discovered to be an essential component of normal human brain development: those born with genes that ...
Choline is a cation with the chemical formula [(CH 3) 3 NCH 2 CH 2 OH] +. [1] [2] [3] Choline forms various salts, such as choline chloride and choline bitartrate.An essential nutrient for animals, it is a structural component of phospholipids and cell membranes.
Phosphatidylcholine is the major component of lecithin. It is also a source for choline in the synthesis of acetylcholine in cholinergic neurons. Phospholipids [ 1 ] are a class of lipids whose molecule has a hydrophilic "head" containing a phosphate group and two hydrophobic "tails" derived from fatty acids , joined by an alcohol residue ...
Phosphorylcholine (abbreviated ChoP) is the hydrophilic polar head group of some phospholipids, which is composed of a negatively charged phosphate bonded to a small, positively charged choline group.
Close regulation of its biosynthesis, degradation, and distribution is essential to proper cell function. Phosphatidylcholine is synthesized in vivo by two pathways The Kennedy pathway, which includes the transformation of choline to citicoline, by way of phosphorylcholine, produces phosphatidylcholine when condensed with diacylglycerol.
[1]: 415 The CDP-choline pathway, first identified by Eugene P. Kennedy in 1956, is the predominant mechanism by which mammalian cells synthesize phosphatidylcholine (PC) for incorporation into membranes or lipid-derived signalling molecules. [1] [2] The CDP-choline pathway represents one half of what is known as the Kennedy pathway.