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Cerebral atrophy is a common feature of many of the diseases that affect the brain. [1] Atrophy of any tissue means a decrement in the size of the cell, which can be due to progressive loss of cytoplasmic proteins. In brain tissue, atrophy describes a loss of neurons and the connections between them.
Neurodegenerative diseases include amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system atrophy, tauopathies, and prion diseases. Neurodegeneration can be found in the brain at many different levels of neuronal circuitry, ranging from molecular to systemic. [4]
A neurological disease refers to any ailment of the central nervous system, including abnormalities of the brain, spinal cord and other connecting nerve fibres. [8] Where millions of people are affected by neurological diseases on a worldwide scale, [8] it has been identified that the number of different types of neurological diseases exceeds six hundred, [9] any of which an individual can incur.
Brain atrophy from vascular dementia: Specialty: Psychiatry, neurology Symptoms: Cognitive impairment, short-term memory loss [3] Complications: Heart disease, loss of ability to care for self and interact, pneumonia [4] Causes: Conditions that impair blood vessels in the brain and therefore interfere with oxygen delivery to the brain [3] Risk ...
An overlap between symptoms can occur as the disease progresses and spreads through the brain regions. [14] Structural MRI scans often reveal frontal lobe and/or anterior temporal lobe atrophy, but in early cases the scan may seem normal. Atrophy can be either bilateral or asymmetric. [13]
Binswanger's disease is a type of subcortical vascular dementia caused by white matter atrophy to the brain. However, white matter atrophy alone is not sufficient for this disease; evidence of subcortical dementia is also necessary. [9] The histologic findings are diffuse, irregular loss of axons and myelin accompanied by widespread gliosis ...
In a trial featuring a mouse model of Alzheimer's, scientists found that inhaling a mixture containing xenon gas helped reduce levels of brain atrophy and neuroinflammation.
In MSA-C, a "hot cross bun" sign is sometimes found; it reflects atrophy of the pontocerebellar tracts that give T2 hyper intense signal intensity in the atrophic pons. MRI changes are not required to diagnose the disease as these features are often absent, especially early in the course of the disease.