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Non-Mendelian inheritance is any pattern in which traits do not segregate in accordance with Mendel's laws. These laws describe the inheritance of traits linked to single genes on chromosomes in the nucleus. In Mendelian inheritance, each parent contributes one of two possible alleles for a trait.
Uniparental inheritance is a non-Mendelian form of inheritance that consists of the transmission of genotypes from one parental type to all progeny. That is, all the genes in offspring will originate from only the mother or only the father.
These epigenetic changes - chemical modifications and markers that change the way enzymes and regulatory proteins have access to DNA - are currently being studied to explain many non-Mendelian patterns of inheritance. The best understood mechanism is nucleotide methylation that silences a gene. Methylation can be inherited during cell division ...
Lethal alleles may specifically refer to embryonically lethal alleles, in which the fetus will never survive to term. Such alleles are a cause of non-Mendelian patterns of inheritance, such as the observation of traits in a 2:1 ratio.
A polygene is a member of a group of non-epistatic genes that interact additively to influence a phenotypic trait, thus contributing to multiple-gene inheritance (polygenic inheritance, multigenic inheritance, quantitative inheritance [1]), a type of non-Mendelian inheritance, as opposed to single-gene inheritance, which is the core notion of Mendelian inheritance.
Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. [11] It is an epigenetic process that involves DNA methylation and histone methylation without altering the genetic sequence.
Biparental inheritance is a type of biological inheritance where the progeny inherits a maternal and a paternal allele for one gene. It is one of the criteria for Mendelian inheritance . Sexual reproduction , where offspring result from the fusion of gametes from two parents, is the most common form of biparental inheritance.
Mendelian inheritance (also known as Mendelism) is a type of biological inheritance following the principles originally proposed by Gregor Mendel in 1865 and 1866, re-discovered in 1900 by Hugo de Vries and Carl Correns, and later popularized by William Bateson. [1] These principles were initially controversial.