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  2. Efficacy - Wikipedia

    en.wikipedia.org/wiki/Efficacy

    Efficacy is the ability to perform a task to a satisfactory or expected degree. The word comes from the same roots as effectiveness , and it has often been used synonymously, although in pharmacology a distinction is now often made between efficacy and effectiveness .

  3. Evidence-based design - Wikipedia

    en.wikipedia.org/wiki/Evidence-based_design

    Evidence-based design (EBD) was popularized by the seminal study by Ulrich (1984) that showed the impact of a window view on patient recovery. [3] Studies have since examined the relationships between design of the physical environment of hospitals with outcomes in health, the results of which show how the physical environment can lower the incidence of nosocomial infections, medical errors ...

  4. Phases of clinical research - Wikipedia

    en.wikipedia.org/wiki/Phases_of_clinical_research

    Determines whether drug is safe to check for efficacy. Phase II: Testing of drug on participants to assess efficacy and side effects Therapeutic dose Clinical researcher 100–300 participants with a specific disease Approx. 28.9% Determines whether drug can have any efficacy; at this point, the drug is not presumed to have any therapeutic effect

  5. Clinical study design - Wikipedia

    en.wikipedia.org/wiki/Clinical_study_design

    Randomized controlled trial [5]. Blind trial [6]; Non-blind trial [7]; Adaptive clinical trial [8]. Platform Trials; Nonrandomized trial (quasi-experiment) [9]. Interrupted time series design [10] (measures on a sample or a series of samples from the same population are obtained several times before and after a manipulated event or a naturally occurring event) - considered a type of quasi ...

  6. Hierarchy of evidence - Wikipedia

    en.wikipedia.org/wiki/Hierarchy_of_evidence

    A large number of hierarchies of evidence have been proposed. Similar protocols for evaluation of research quality are still in development. So far, the available protocols pay relatively little attention to whether outcome research is relevant to efficacy (the outcome of a treatment performed under ideal conditions) or to effectiveness (the outcome of the treatment performed under ordinary ...

  7. Formulary (pharmacy) - Wikipedia

    en.wikipedia.org/wiki/Formulary_(pharmacy)

    A formulary is a list of pharmaceutical drugs, often decided upon by a group of people, for various reasons such as insurance coverage or use at a medical facility. [1] Traditionally, a formulary contained a collection of formulas for the compounding and testing of medication (a resource closer to what would be referred to as a pharmacopoeia ...

  8. EC50 - Wikipedia

    en.wikipedia.org/wiki/EC50

    Efficacy is the relationship between receptor occupancy and the ability to initiate a response at the molecular, cellular, tissue or system level.

  9. Outcome measure - Wikipedia

    en.wikipedia.org/wiki/Outcome_measure

    An outcome measure, endpoint, effect measure or measure of effect is a measure within medical practice or research, (primarily clinical trials) which is used to assess the effect, both positive and negative, of an intervention or treatment. [1] [2] Measures can often be quantified using effect sizes. [3]