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Micrograph showing apocrine metaplasia of the breast with typical features, [4] including apical snouts with eosinophilic granules. H&E stain. Apocrine metaplasia is a reversible transformation of cells to an apocrine phenotype. It is common in the breast in the context of fibrocystic change. It is seen in women mostly over the age of 50 years.
Goblet cells are simple columnar epithelial cells, having a height of four times that of their width. The cytoplasm of goblet cells tends to be displaced toward the basal end of the cell body by the large mucin granules, which accumulate near the apical surface of the cell along the Golgi apparatus, which lies between the granules and the nucleus.
An apocrine sweat gland (/ ˈ æ p ə k r ə n,-ˌ k r aɪ n,-ˌ k r iː n /; from Greek apo 'away' and krinein 'to separate') [5] [6] is composed of a coiled secretory portion located at the junction of the dermis and subcutaneous fat, from which a straight portion inserts and secretes into the infundibular portion of the hair follicle. [7]
Micrograph showing apocrine metaplasia of the breast with typical features [3] H&E stain. Barrett's esophagus is an abnormal change in the cells of the lower esophagus, thought to be caused by damage from chronic stomach acid exposure. The following table lists some common tissues susceptible to metaplasia, and the stimuli that can cause the ...
Both apocrine and eccrine sweat glands use merocrine secretion, where vesicles in the gland release sweat via exocytosis, leaving the entire cell intact. [ 37 ] [ 7 ] It was originally thought that apocrine sweat glands use apocrine secretion due to histological artifacts resembling "blebs" on the cell surface, however, recent electron ...
Myoepithelial cells (sometimes referred to as myoepithelium) are cells usually found in glandular epithelium as a thin layer above the basement membrane but generally beneath the luminal cells. These may be positive for alpha smooth muscle actin and can contract and expel the secretions of exocrine glands .
Metaplasia occurs when a cell of a certain type is replaced by another cell type, which may be less differentiated. It is a reversible process thought to be caused by stem cell reprogramming. Stem cells are found in epithelia and embryonic mesenchyme of connective tissue. A prominent example of metaplasia involves the changes associated with ...
Apocrine metaplasia. Pathology Outlines. Last author update: 28 May 2020; Author: Mikael Häggström, M.D. Author info - Reusing images - Conflicts of interest: