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Gallbladder cancer is a relatively uncommon cancer, with an incidence of fewer than 2 cases per 100,000 people per year in the United States. [7] It is particularly common in central and South America, central and eastern Europe, Japan and northern India; it is also common in certain ethnic groups e.g. Native American Indians and Hispanics. [8]
[27] Removal of the gallbladder with surgery, known as a cholecystectomy, is the definitive surgical treatment for biliary colic. [28] A 2013 Cochrane review found tentative evidence to suggest that early gallbladder removal may be better than delayed removal. [29] Early laparoscopic cholecystectomy happens within 72 hours of diagnosis. [13]
Gallbladder diseases are diseases involving the gallbladder and is closely linked to biliary disease, with the most common cause being gallstones (cholelithiasis). [1] [2]The gallbladder is designed to aid in the digestion of fats by concentrating and storing the bile made in the liver and transferring it through the biliary tract to the digestive system through bile ducts that connect the ...
Rapid weight loss increases risk of gallstones. [27] The weight loss drug orlistat is known to increase the risk of gallstones. [28] Cholecystokinin deficiency caused by celiac disease increases risk of gallstone formation, especially when diagnosis of celiac disease is delayed. [29] Pigment gallstones are most commonly seen in the developing ...
Although unusual, it is possible to have a common bile duct stone despite prior cholecystectomy. One study found that in patients diagnosed with choledocholithiasis, 28% had undergone prior cholecystectomy. Such stones are thought to be the result of stones missed at the time of the cholecystectomy, as opposed to the formation of new stones. [3]
Diseases of the gallbladder and bile ducts are commonly diet-related, and may include the formation of gallstones that impact in the gallbladder (cholecystolithiasis) or in the common bile duct (choledocholithiasis). [5]: 977–978 Gallstones are a common cause of inflammation of the gallbladder, called cholecystitis.
Exercise helps to maintain a healthy weight and counters the loss in muscle mass that accompanies weight loss, according to Mayo Clinic. U.S. News & World Report 2024 Best Diet rankings
The most common physical indications of cholangiocarcinoma are abnormal liver function tests, jaundice (yellowing of the eyes and skin occurring when bile ducts are blocked by tumor), abdominal pain (30–50%), generalized itching (66%), weight loss (30–50%), fever (up to 20%), and changes in the color of stool or urine. [10]