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Anthelmintic medication is also used in mass deworming campaigns of school-aged children in many developing countries. [2] [3] Anthelmintics are also used for mass deworming of livestock. The drugs of choice for soil-transmitted helminths are mebendazole and albendazole; [4] for schistosomiasis and tapeworms it is praziquantel. [5]
Dosage is 11 mg/kg not to exceed 1 g as a single dose. [citation needed] Albendazole, a broad-spectrum antihelminthic agent that decreases ATP production in the worm, causing energy depletion, immobilization, and finally death. Dosage is 400 mg given as single oral dose (contraindicated during pregnancy and children under 2 years).
It is a member of the benzimidazole family of medications for worms. [1] Triclabendazole was approved for medical use in the United States in 2019. [3] [4] It is on the World Health Organization's List of Essential Medicines. [5] For human use, it can be obtained from the World Health Organization. [2] It is also used in animals. [6]
Albendazole is a broad-spectrum antihelmintic and antiprotozoal agent of the benzimidazole type. [3] It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases.
Side effects in humans may include poor coordination, abdominal pain, vomiting, headache, and allergic reactions. [4] While it may be used during pregnancy, it is not recommended for use during breastfeeding. [4] Praziquantel is in the anthelmintic class of medications. [3] It works partly by affecting the function of the worm's sucker. [3]
Mebendazole (MBZ), sold under the brand name Vermox among others, is a medication used to treat a number of parasitic worm infestations. [5] This includes ascariasis, pinworm infection, hookworm infections, guinea worm infections and hydatid disease, among others. [5] It has been used for treatment of giardiasis but is not a preferred agent.
A lower dose should be used in people with liver disease. [2] While it does not appear to be harmful during pregnancy, it has not been studied for this use. [3] It is unclear if it is safe for use during breastfeeding. [2] It is in the antihelmintic family of medications. [4] It works by paralyzing worms. [4] Pyrantel was initially described in ...
The treatment is given as a single dose in a pill formulation. [3] [5] Other drugs used, though not approved by the WHO, include pyrantel pamoate, piperazine, piperazine citrate, tetrachloroethylene, and levamisole. [3] In mass deworming programs, all children are given the medication, whether they are infected or not.