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Hershey was born in Owosso, Michigan to Robert Day and Alma Wilbur Hershey. He earned a B.S. in chemistry in 1930, and Ph.D. in bacteriology in 1934 from Michigan State University. Shortly after, Hershey accepted a faculty position at Washington University in St. Louis, [1] [2] serving as an instructor of bacteriology and immunology from 1934 ...
Martha Cowles Chase (November 30, 1927 – August 8, 2003), also known as Martha C. Epstein, [1] was an American geneticist who in 1952, with Alfred Hershey, experimentally helped to confirm that DNA rather than protein is the genetic material of life.
Scientist Martha Chase and Alfred Hershey While DNA had been known to biologists since 1869, [ 2 ] many scientists still assumed at the time that proteins carried the information for inheritance because DNA appeared to be an inert molecule, and, since it is located in the nucleus, its role was considered to be phosphorus storage.
Formed in 1945 and led by Delbrück along with Salvador Luria and Alfred Hershey, the Phage Group made substantial headway unraveling important aspects of genetics. The three shared the 1969 Nobel Prize in Physiology or Medicine "for their discoveries concerning the replication mechanism and the genetic structure of viruses". [3]
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In 1952, Alfred Hershey and Martha Chase confirmed that the genetic material of the bacteriophage, the virus which infects bacteria, is made up of DNA [4] (see Hershey–Chase experiment). In 1953, James Watson and Francis Crick discovered the double helical structure of the DNA molecule based on the discoveries made by Rosalind Franklin. [5]
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Alfred Hershey and Martha Chase furthered Avery's research in 1952 with the Hershey–Chase experiment. These experiments paved the way for Watson and Crick's discovery of the helical structure of DNA, and thus the birth of modern genetics and molecular biology. Of this event, Avery wrote in a letter to his youngest brother Roy, a ...