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The Golgi tendon reflex operates as a protective feedback mechanism to control the tension of an active muscle by causing relaxation before the tendon tension becomes high enough to cause damage. [7] First, as a load is placed on the muscle, the afferent neuron from the Golgi tendon organ fires into the central nervous system.
The Golgi tendon organ (GTO) (also called Golgi organ, tendon organ, neurotendinous organ or neurotendinous spindle) is a proprioceptor – a type of sensory receptor that senses changes in muscle tension. It lies at the interface between a muscle and its tendon known as the musculotendinous junction also known as the myotendinous junction. [1]
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Golgi's method is a silver staining technique that is used to visualize nervous tissue under light microscopy. The method was discovered by Camillo Golgi , an Italian physician and scientist , who published the first picture made with the technique in 1873. [ 1 ]
A free nerve ending (FNE) or bare nerve ending, is an unspecialized, afferent nerve fiber sending its signal to a sensory neuron. Afferent in this case means bringing information from the body's periphery toward the brain. They function as cutaneous nociceptors and are essentially used by vertebrates to detect noxious stimuli that often result ...
The sensory endings of a primary (group Ia) afferent and a secondary (group II) afferent coil around the non-contractile central portions of the intrafusal fibres. Gamma motor neurons activate the intrafusal muscle fibres, changing the resting firing rate and stretch-sensitivity of the afferents.
Camillo Golgi (Italian: [kaˈmillo ˈɡɔldʒi]; 7 July 1843 – 21 January 1926) was an Italian biologist and pathologist known for his works on the central nervous system.He studied medicine at the University of Pavia (where he later spent most of his professional career) between 1860 and 1868 under the tutelage of Cesare Lombroso.
Axon terminals are specialized to release neurotransmitters very rapidly by exocytosis. [1] Neurotransmitter molecules are packaged into synaptic vesicles that cluster beneath the axon terminal membrane on the presynaptic side (A) of a synapse.