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  2. Preload (cardiology) - Wikipedia

    en.wikipedia.org/wiki/Preload_(cardiology)

    In cardiac physiology, preload is the amount of sarcomere stretch experienced by cardiac muscle cells, called cardiomyocytes, at the end of ventricular filling during diastole. [1] Preload is directly related to ventricular filling.

  3. Pressure–volume loop analysis in cardiology - Wikipedia

    en.wikipedia.org/wiki/Pressure–volume_loop...

    Afterload is the mean tension produced by a chamber of the heart in order to contract. It can also be considered as the ‘load’ that the heart must eject blood against. Afterload is, therefore, a consequence of aortic large vessel compliance, wave reflection, and small vessel resistance (LV afterload) or similar pulmonary artery parameters (RV afterload

  4. End-diastolic volume - Wikipedia

    en.wikipedia.org/wiki/End-diastolic_volume

    Because greater EDVs cause greater distention of the ventricle, EDV is often used synonymously with preload, which refers to the length of the sarcomeres in cardiac muscle prior to contraction . An increase in EDV increases the preload on the heart and, through the Frank-Starling mechanism of the heart, increases the amount of blood ejected ...

  5. Frank–Starling law - Wikipedia

    en.wikipedia.org/wiki/Frank–Starling_law

    As a larger volume of blood flows into the ventricle, the blood stretches cardiac muscle, leading to an increase in the force of contraction. The Frank-Starling mechanism allows the cardiac output to be synchronized with the venous return, arterial blood supply and humoral length, [2] without depending upon external regulation to make ...

  6. Cardiac physiology - Wikipedia

    en.wikipedia.org/wiki/Cardiac_physiology

    Cardiac physiology or heart function is the study of healthy, unimpaired function of the heart: involving blood flow; ... (EDV) or preload. [1] Initially, as the ...

  7. Cardiac output - Wikipedia

    en.wikipedia.org/wiki/Cardiac_output

    Major factors influencing cardiac output – heart rate and stroke volume, both of which are variable. [1]In cardiac physiology, cardiac output (CO), also known as heart output and often denoted by the symbols , ˙, or ˙, [2] is the volumetric flow rate of the heart's pumping output: that is, the volume of blood being pumped by a single ventricle of the heart, per unit time (usually measured ...

  8. Central venous pressure - Wikipedia

    en.wikipedia.org/wiki/Central_venous_pressure

    Trend of central venous pressure as a consequence of variations in cardiac output. The three functions indicate the trend in physiological conditions (in the centre), in those of decreased preload (e.g. in hemorrhage, bottom curve) and in those of increased preload (e.g. following transfusion, top curve).

  9. Myocardial contractility - Wikipedia

    en.wikipedia.org/wiki/Myocardial_contractility

    An increase in sympathetic stimulation to the heart increases contractility and heart rate. An increase in contractility tends to increase stroke volume and thus a secondary increase in preload. An increase in preload results in an increased force of contraction by Starling's law of the heart; this does not require a change in contractility.