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A bioresorbable stent is a tube-like device that is used to open and widen clogged heart arteries and then dissolves or is absorbed by the body. It is made from a material that can release a drug to prevent scar tissue growth. It can also restore normal vessel function and avoid long-term complications of metal stents. [1] [2]
Bioresorbable (also called biodegradable or bioabsorbable) metals are metals or their alloys that degrade safely within the body. [1] The primary metals in this category are magnesium-based [ 2 ] [ 3 ] and iron-based alloys, [ 4 ] although recently zinc has also been investigated.
Although the polymer was originally designed for biodegradable sutures, PolyAspirin is now undergoing clinical trials as a material for a new type of cardiac stent. This biodegradable stent controls the inflammation effects occurring after angioplasty, called restenosis and disappears when no longer needed. [7] [8] Kathryn Uhrich at Rutgers
The Genous Stent is a bio-engineered coronary stent coated with immobilized anti-CD34 monoclonal antibodies specific to the Genous technology. [3] [4] The Combo Dual Therapy Stent is a coronary stent that combines Genous with an antiproliferative, biodegradable sirolimus drug elution.
Nitinol biocompatibility is an important factor in biomedical applications.Nitinol (NiTi), which is formed by alloying nickel and titanium (~ 50% Ni), is a shape-memory alloy with superelastic properties more similar to that of bone, [clarification needed] when compared to stainless steel, another commonly used biomaterial.
Coronary stents are placed during a coronary angioplasty.The most common use for coronary stents is in the coronary arteries, into which a bare-metal stent, a drug-eluting stent, a bioabsorbable stent, a dual-therapy stent (combination of both drug and bioengineered stent), or occasionally a covered stent is inserted.
Metallic glasses based on magnesium with zinc and calcium addition are tested as the potential biocompatible metallic biomaterials for biodegradable medical implants [14] Biocompatibility (or tissue compatibility) describes the ability of a material to perform with an appropriate host response when applied as intended.
(right forearm) A coronary stent — in this case a drug-eluting stent — is another common item implanted in humans. An implant is a medical device manufactured to replace a missing biological structure, support a damaged biological structure, or enhance an existing biological structure.