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  2. Immunoglobulin M - Wikipedia

    en.wikipedia.org/wiki/Immunoglobulin_M

    Immunoglobulin M (IgM) is the largest of several isotypes of antibodies (also known as immunoglobulin) that are produced by vertebrates. IgM is the first antibody to appear in the response to initial exposure to an antigen ; [ 1 ] [ 2 ] causing it to also be called an acute phase antibody.

  3. Coombs test - Wikipedia

    en.wikipedia.org/wiki/Coombs_test

    IgG antibodies are most reactive at 37°C. IgM antibodies are easily detected in saline at room temperature as IgM antibodies are able to bridge between RBC's owing to their large size, efficiently creating what is seen as agglutination. IgG antibodies are smaller and require assistance to bridge well enough to form a visual agglutination ...

  4. Antiganglioside antibodies - Wikipedia

    en.wikipedia.org/wiki/Antiganglioside_antibodies

    Antiganglioside antibodies that react to self-gangliosides are found in autoimmune neuropathies. These antibodies were first found to react with cerebellar cells . [ 1 ] These antibodies show highest association with certain forms of Guillain–Barré syndrome .

  5. Seroconversion - Wikipedia

    en.wikipedia.org/wiki/Seroconversion

    Anti-core antibodies (anti-HBc) are the first antibodies produced by the body, first in short-term IgM (anti-HBc IgM), and subsequently in long-term IgG; while levels of IgM anti-HBc will peak around sixteen weeks after exposure and fall within about seven to eight months, [63] [64] IgG anti-HBc will remain detectable in the serum as a sign of ...

  6. Anti-MAG peripheral neuropathy - Wikipedia

    en.wikipedia.org/wiki/Anti-MAG_peripheral_neuropathy

    Anti-MAG antibodies can be readily detected in a patient's sera using various types of assays, but mainly an ELISA has been shown to be most effective. [ 1 ] [ 8 ] There are also various biological indicators, such as elevated cerebral spinal fluid proteins and elevated IgM monoclonal levels.

  7. ABO blood group system - Wikipedia

    en.wikipedia.org/wiki/ABO_blood_group_system

    The associated anti-A and anti-B antibodies are usually IgM antibodies, produced in the first years of life by sensitization to environmental substances such as food, bacteria, and viruses. The ABO blood types were discovered by Karl Landsteiner in 1901; he received the Nobel Prize in Physiology or Medicine in 1930 for this discovery. [ 5 ]