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The TSH, in turn, stimulates the thyroid to produce thyroid hormone until levels in the blood return to normal. Thyroid hormone exerts negative feedback control over the hypothalamus as well as anterior pituitary, thus controlling the release of both TRH from hypothalamus and TSH from anterior pituitary gland. [2]
They can be classified as a hypothalamic–pituitary axis (HP axis) of which the adrenal (HPA Tooltip hypothalamic–pituitary–adrenal axis), gonadal (HPG Tooltip hypothalamic–pituitary–gonadal axis), thyroid (HPT Tooltip hypothalamic–pituitary–thyroid axis), somatotropic (HPS Tooltip hypothalamic–pituitary–somatotropic axis), and ...
Hypothalamic interaction with the posterior and anterior pituitary glands. The hypothalamus produces the hormones oxytocin and vasopressin in its endocrine cells (left). These are released at nerve endings in the posterior pituitary gland and then secreted into the systemic circulation.
The hypophyseal portal system is a system of blood vessels in the microcirculation at the base of the brain, connecting the hypothalamus with the anterior pituitary. Its main function is to quickly transport and exchange hormones between the hypothalamus arcuate nucleus and anterior pituitary gland.
Later and expanded versions of the software were used to develop the hypothesis of the TSH-T3 shunt in the hypothalamus-pituitary-thyroid axis, [10] to assess the validity of calculated parameters of thyroid homeostasis (including SPINA-GT and SPINA-GD) [11] [12] and to study allostatic mechanisms leading to non-thyroidal illness syndrome. [13 ...
The hypothalamic-pituitary-thyroid axis. TRH can be seen in green. TRH is synthesized within parvocellular neurons of the paraventricular nucleus of the hypothalamus. [2] It is translated as a 242-amino acid precursor polypeptide that contains 6 copies of the sequence -Gln-His-Pro-Gly-, with both ends of the sequence flanked by Lys-Arg or Arg-Arg sequences.
THRB mutation directly affects the regulation of the hypothalamic-pituitary-thyroid (HPT) axis. In a healthy individual, the TR-β2 expressed in the pituitary gland plays a major role in regulating thyroid-stimulating hormone (TSH) levels through negative feedback. TSH stimulates the thyroid to secrete thyroid hormone.
Pages in category "Hormones of the hypothalamus-pituitary-thyroid axis" The following 8 pages are in this category, out of 8 total. This list may not reflect recent changes .