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Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age. [14] The syndrome is named after cysts which form on the ovaries of some women with this condition, though this is not a universal symptom and not the underlying cause of the disorder.
MDCalc was founded by two emergency physicians, Graham Walker, MD, and Joseph Habboushe, MD, MBA, [5] and provides over 500 medical calculators and other clinical decision-support tools. [6] The MDCalc.com website was launched in 2005. [5] In 2016, MDCalc launched an iOS app, [7] followed by an Android app in 2017. [8]
Insulin resistance leads to hyperinsulinemia which, in turn, leads to an excess production of androgen hormones by the ovaries. High levels of androgen hormones (hyperandrogenism) in females causes excessive hair growth, acne and irregular menstruation. Patients with both underlying mechanisms of insulin resistance may have more severe ...
Hyperandrogenism is a medical condition characterized by high levels of androgens.It is more common in women than men. [4] Symptoms of hyperandrogenism may include acne, seborrhea, hair loss on the scalp, increased body or facial hair, and infrequent or absent menstruation.
Not all women with PCOS have difficulty becoming pregnant. For those who do, anovulation is a common cause. The mechanism of this anovulation is uncertain, but there is evidence of arrested antral follicle development, which, in turn, may be caused by abnormal interaction of insulin and luteinizing hormone (LH) on granulosa cells.
On a single-step or immediate-execution calculator, the user presses a key for each operation, calculating all the intermediate results, before the final value is shown. [1] [2] [3] On an expression or formula calculator, one types in an expression and then presses a key, such as "=" or "Enter", to evaluate the expression.
Seen as a severe form of PCOS, the clinical features of hyperthecosis are similar to those of PCOS. [3] Women with hyperthecosis often have more markedly elevated testosterone, more hirsutism, and are much more likely to be virilized. [ 4 ]
Calculators supporting such programming were Turing-complete if they supported both conditional statements and indirect addressing of memory. Notable examples of Turing complete calculators were Casio FX-602P series, the HP-41 and the TI-59. Keystroke programming is still used in mid-range calculators like the HP 35s and HP-12C.