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Erythromelalgia, or Mitchell's disease (after Silas Weir Mitchell), is a rare vascular peripheral pain disorder in which blood vessels, usually in the lower extremities or hands, are episodically blocked (frequently on and off daily), then become hyperemic and inflamed. There is severe burning pain (in the small fiber sensory nerves) and skin ...
Raynaud’s disease is a rare peripheral vascular syndrome that narrows blood vessels, generally in the hands and feet, due to cold or stressful emotion. [8] It is recognized by the reduction of blood flow to fingers and toes with periodic spasm and results in a drastic color change to white or blue.
Thromboangiitis obliterans, also known as Buerger disease (English / ˈ b ɜːr ɡ ər /; German: [ˈbʏʁɡɐ]) or Winiwarter-Buerger disease, is a recurring progressive inflammation and thrombosis (clotting) of small and medium arteries and veins of the hands and feet.
[5] [43] This causes blood to back up. [5] Excess fluid leaks from the capillaries into the spaces between the soft tissue's cells. [44] This swells the extracellular space and raises the pressure in the compartment. [5] [7] The swelling of the soft tissues around the blood vessels compresses the blood and lymphatic vessels.
There are a number of other causes for splinter hemorrhages. They could be due to hitting the nail (trauma), a sign of inflammation in blood vessels all around the body (systemic vasculitis), or they could be where a fragment of cholesterol has become lodged in the capillaries of the finger. Even if a patient does have infective endocarditis ...
The cause of this is not well understand but it's generally thought to be something to do with serotonin. Gut microbes modulate about 60% of your serotonin so that you can use it, and antibiotics ...
The diagnosis of Flammer syndrome is primarily based on the patient's history with its typical features as well as the findings of nail fold capillaroscopy. This test shows an excessive constriction (narrowing) in the smallest blood vessels (capillaries) of the fingers in response to being exposed to cold.
In the microcirculation consisting of the very small and smallest blood vessels, the capillaries, tiny thrombi (microthrombi) [5] known as microclots can obstruct the flow of blood in the capillaries. Microclots are small clumps of blood that form within the circulation, usually as a result of a larger thrombus breaking down into smaller pieces.