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Stercoral ulcer is an ulcer of the colon due to pressure and irritation resulting from severe, prolonged constipation due to a large bowel obstruction, damage to the autonomic nervous system, or stercoral colitis. It is most commonly located in the sigmoid colon and rectum.
A high-fiber diet may help, but by itself is insufficient treatment. 30 to 40 grams of fiber per day has been advised. [13] Improvement with high-fiber diet varies between 19% and 70%. [1] Bulk forming laxatives, [8] e.g. psyllium powder. [4] Stool softeners. [8] Adequate intake of water (non-carbonated and caffeine-free drinks) during the day. [5]
Management of ulcerative colitis involves first treating the acute symptoms of the disease, then maintaining remission. Ulcerative colitis is a form of colitis, a disease of the intestine, specifically the large intestine or colon, that includes characteristic ulcers, or open sores, in the colon.
An anti-TL1A monoclonal antibody called tulisokibart may help people with moderate to severe ulcerative colitis achieve clinical remission, a phase 2 trial has found.
Ulcerative colitis is a type of inflammatory bowel disease (IBD). [4] It is a long-term condition that results in inflammation and ulcers of the colon and rectum. [4] [5] The primary symptoms of active disease are abdominal pain and diarrhea mixed with blood (hematochezia).
Although the use of antibodies to treat diseases can be dated back to the 1800s, biologic therapy as we know it today is a relatively new concept for the treatment of inflammatory bowel disease. [9] The previous treatment options had many shortcomings, and the introduction of biological therapy changed the way physicians treat Crohn's disease ...