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Alezzandrini syndrome is a very rare syndrome characterized by a unilateral degenerative retinitis, followed after several months by ipsilateral vitiligo on the face and ipsilateral poliosis. [1]: 864 [2] Deafness may also be present. [1]: 864 [3]
Neoplasms and medication-induced poliosis: Poliosis has been associated with melanocytic lesions such as congenital or acquired nevi and melanoma. Additionally, poliosis is a rare side effect of certain medications, including topical prostaglandin analogs (used in glaucoma treatment) and systemic drugs like chloroquine and acitretin .
Waardenburg syndrome has multiple different types with some variations in symptoms, and symptoms can vary among those with the same type. The two features consistent across all types of Waardenburg syndrome are some degree of congenital sensorineural hearing loss and some degree of pigmentation deficiencies, most consistently in the eyes.
Uveitis with poliosis of the eyelashes. The disease is characterised by bilateral diffuse uveitis, with pain, redness and blurring of vision.The eye symptoms may be accompanied by a varying constellation of systemic symptoms, such as auditory (tinnitus, [6] vertigo, [6] and hypoacusis), neurological (meningismus, with malaise, fever, headache, nausea, abdominal pain, stiffness of the neck and ...
[19] [20] Clinically, the diagnosis of any particular skin condition is made by gathering pertinent information regarding the presenting skin lesion(s), including the location (such as arms, head, legs), symptoms (pruritus, pain), duration (acute or chronic), arrangement (solitary, generalized, annular, linear), morphology (macules, papules ...
The pigment loss can be partial (injury to the skin) or complete (caused by vitiligo). It can be temporary (from tinea versicolor) or permanent (from albinism). [1] Most commonly, depigmentation of the skin is linked to people born with vitiligo, which produces differing areas of light and dark skin. Monobenzone also causes skin depigmentation.