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A pericardial effusion is an abnormal accumulation of fluid in the pericardial cavity. The pericardium is a two-part membrane surrounding the heart: the outer fibrous connective membrane and an inner two-layered serous membrane. The two layers of the serous membrane enclose the pericardial cavity (the potential space) between them. [1]
Postpericardiotomy syndrome (PPS) is a medical syndrome referring to an immune phenomenon that occurs days to months (usually 1–6 weeks [1]) after surgical incision of the pericardium (membranes encapsulating the human heart). [2] PPS can also be caused after a trauma, a puncture of the cardiac or pleural structures (such as a bullet or stab ...
Cardiac tamponade, also known as pericardial tamponade (/ ˌtæm.pəˈneɪd / [ 4 ]), is a compression of the heart due to pericardial effusion (the build-up of pericardial fluid in the sac around the heart). [ 2 ] Onset may be rapid or gradual. [ 2 ] Symptoms typically include those of obstructive shock including shortness of breath, weakness ...
Hemopericardium is a condition that affects the cardiovascular system. It typically begins with blood accumulating in the pericardial sac posterior to the heart, and eventually expands to surround the entire heart. [6] The fluid build-up then causes pressure within the pericardial sac to increase. If the pressure becomes greater than the ...
Drug delivery to the brain. Drug delivery to the brain is the process of passing therapeutically active molecules across the blood–brain barrier into the brain. This is a complex process that must take into account the complex anatomy of the brain as well as the restrictions imposed by the special junctions of the blood–brain barrier.
Dressler syndrome. Dressler syndrome is a secondary form of pericarditis that occurs in the setting of injury to the heart or the pericardium (the outer lining of the heart). It consists of fever, pleuritic pain, pericarditis and/or pericardial effusion. Dressler syndrome is also known as postmyocardial infarction syndrome[1] and the term is ...
The blood–brain barrier (BBB) is a highly selective semipermeable border of endothelial cells that regulates the transfer of solutes and chemicals between the circulatory system and the central nervous system, thus protecting the brain from harmful or unwanted substances in the blood. [1] The blood–brain barrier is formed by endothelial ...
More than 50% of cases have some sort of extraskeletal involvement. This can include kidney, skin, brain and lung involvement, and less frequently retroorbital tissue, pituitary gland and heart involvement is observed. [3] Bone pain is the most frequent of all symptoms associated with ECD and mainly affects the lower limbs, knees and ankles.
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