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Organic synthesis is a branch of chemical synthesis concerned with the construction of organic compounds. Organic compounds are molecules consisting of combinations of covalently-linked hydrogen, carbon, oxygen, and nitrogen atoms. Within the general subject of organic synthesis, there are many different types of synthetic routes that can be ...
Elias James Corey (born July 12, 1928) is an American organic chemist. In 1990, he won the Nobel Prize in Chemistry "for his development of the theory and methodology of organic synthesis ", [3] specifically retrosynthetic analysis. [4][5] Regarded by many as one of the greatest living chemists, he has developed numerous synthetic reagents ...
Chemical synthesis (chemical combination) is the artificial execution of chemical reactions to obtain one or several products. [1] This occurs by physical and chemical manipulations usually involving one or more reactions. In modern laboratory uses, the process is reproducible and reliable. A chemical synthesis involves one or more compounds ...
Synthetic organic chemistry is an applied science as it borders engineering, the "design, analysis, and/or construction of works for practical purposes". Organic synthesis of a novel compound is a problem-solving task, where a synthesis is designed for a target molecule by selecting optimal reactions from optimal starting materials.
In organic chemistry, peptide synthesis is the production of peptide molecules by chemical means. Formally, alpha- amino acids are condensed with the exclusion of water molecules, to form linear chains in which the amino acids are linked by amide bonds. The amide bond between two alpha amino acids is known as a peptide bond.
Solid-phase synthesis is a common technique for peptide synthesis. Usually, peptides are synthesised from the carbonyl group side (C-terminus) to amino group side (N-terminus) of the amino acid chain in the SPPS method, although peptides are biologically synthesised in the opposite direction in cells. In peptide synthesis, an amino-protected ...