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The progenitor notochord is derived from cells migrating from the primitive node and pit. [9] The notochord forms during gastrulation and soon after induces the formation of the neural plate (neurulation), synchronizing the development of the neural tube. On the ventral aspect of the neural groove, an axial thickening of the endoderm takes place.
The neural plate switches from E-cadherin expression to N-cadherin and N-CAM expression to recognize each other as the same tissue and close the tube. This change in expression stops the binding of the neural tube to the epidermis. The notochord plays an integral role in the development of the neural tube.
1.3 Neural tube. 1.3.1 Central nervous ... lateral plate mesoderm and notochord). Also showing the neural tube and the yolk sac. ... Cardiac muscle cell; Other ...
Histologically, these cells are classified as pseudostratified columnar cells. [ 1 ] After recruitment from the ectoderm, the neuroectoderm undergoes three stages of development: transformation into the neural plate , transformation into the neural groove (with associated neural folds ), and transformation into the neural tube .
Both processes position neural crest cells between a superficial epidermal layer and the deep neural tube. During primary neurulation, the notochord cells of the mesoderm signal the adjacent, superficial ectoderm cells to reposition themselves into a columnar pattern to form cells of the ectodermal neural plate . [ 7 ]
Paraxial mesoderm, also known as presomitic or somitic mesoderm, is the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites, blocks of tissue running along both sides of the neural tube, which form muscle and the tissues of the back, including ...
Splits or pockets may form in the germinal sheet of cells forming vesicles or elongations. The lungs and glands of the organism may develop this way. [6] A primary step in organogenesis for chordates is the development of the notochord, which induces the formation of the neural plate, and ultimately the neural tube in
The ventral part of the neural tube contains the basal plate, which is primarily associated with motor (i.e., muscle) control. The spinal cord develops from the posterior neural tube. As the spinal cord develops, the cells making up the wall of the neural tube proliferate and differentiate into the neurons and glia of the spinal cord.