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  2. Pilocarpine - Wikipedia

    en.wikipedia.org/wiki/Pilocarpine

    Use of pilocarpine may result in a range of adverse effects, most of them related to its non-selective action as a muscarinic receptor agonist. Pilocarpine has been known to cause excessive salivation, sweating, bronchial mucus secretion, bronchospasm, bradycardia, vasodilation, and diarrhea. Eye drops can result in brow ache and chronic use in ...

  3. Ophthalmic drug administration - Wikipedia

    en.wikipedia.org/wiki/Ophthalmic_drug_administration

    Figure 1.0 - Basic anatomical features of the human eye. Ophthalmic drug administration is the administration of a drug to the eyes, most typically as an eye drop formulation. Topical formulations are used to combat a multitude of diseased states of the eye. These states may include bacterial infections, eye injury, glaucoma, and dry eye. [1]

  4. Glaucoma - Wikipedia

    en.wikipedia.org/wiki/Glaucoma

    The first drug to reduce IOP, pilocarpine, was introduced in the 1870s; other major innovations in pharmacological glaucoma therapy were the introduction of beta blocker eye drops in the 1970s and of prostaglandin analogues and topical (locally administered) carbonic anhydrase inhibitors in the mid-1990s. Early surgical techniques like ...

  5. Glaucoma medication - Wikipedia

    en.wikipedia.org/wiki/Glaucoma_medication

    Dosage IOP decrease Side effects Prostaglandin analogs: Latanoprost: Xalatan: Increased USO (uveoscleral outflow ) Once daily: 25-32%: pigmentation of eyelashes, eyelid skin pigmentation, hyperemia (red eye), flu-like symptoms (joint/muscle pain and headache) Bimatoprost: Lumigan: Increased USO (uveoscleral outflow ) Once daily

  6. Tropicamide - Wikipedia

    en.wikipedia.org/wiki/Tropicamide

    Tropicamide, sold under the brand name Mydriacyl among others, is a medication used to dilate the pupil and help with examination of the eye. [3] Specifically it is used to help examine the back of the eye. [4] It is applied as eye drops. [3] Effects occur within 40 minutes and last for up to a day. [3]

  7. Muscarinic agonist - Wikipedia

    en.wikipedia.org/wiki/Muscarinic_agonist

    Pilocarpine is a drug that acts as a muscarinic receptor agonist that is used to treat glaucoma Cevimeline (AF102B) (Evoxac®) is a muscarinic agonist that is a Food and Drug Administration (FDA)- approved drug and used for the management of dry mouth in Sjögren's syndrome