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Antineoplastic resistance, often used interchangeably with chemotherapy resistance, is the resistance of neoplastic (cancerous) cells, or the ability of cancer cells to survive and grow despite anti-cancer therapies. [1] In some cases, cancers can evolve resistance to multiple drugs, called multiple drug resistance.
Podophyllotoxin is an antineoplastic lignan obtained primarily from the American mayapple (Podophyllum peltatum) and Himalayan mayapple (Sinopodophyllum hexandrum). It has anti-microtubule activity, and its mechanism is similar to that of vinca alkaloids in that they bind to tubulin, inhibiting microtubule formation.
Cell-cycle nonspecific antineoplastic agents; Chemically linked Fab; Chemoimmunotherapy; Chemoprotective agent; Chemosensitizer; Chemotherapy; Chemotherapy-induced nausea and vomiting; Ciltacabtagene autoleucel; Copanlisib; Cytestrol acetate
An alkylating antineoplastic agent is an alkylating agent used in cancer treatment that attaches an alkyl group (C n H 2n+1) to DNA. [1] Since cancer cells, in general, proliferate faster and with less error-correcting than healthy cells, cancer cells are more sensitive to DNA damage—such as being alkylated. Alkylating agents are used to ...
This is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer.This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision.
Platinum-based antineoplastic drugs (informally called platins) are chemotherapeutic agents used to treat cancer. Their active moieties are coordination complexes of platinum . These drugs are used to treat almost half of people receiving chemotherapy for cancer.
Antineoplastic drugs (17 C, 201 P) C. Cereblon E3 ligase modulators (7 P) I. Immunomodulating drugs (6 C, 25 P)