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In the anatomy of the brain of vertebrates, the forebrain or prosencephalon is the rostral (forward-most) portion of the brain.The forebrain controls body temperature, reproductive functions, eating, sleeping, and the display of emotions.
These structures are important in producing the neurotransmitter, acetylcholine, which is then distributed widely throughout the brain. The basal forebrain, in particular the nucleus basalis, is considered to be the major cholinergic output of the central nervous system to the striatum and neocortex. [31]
The limbic system, also known as the paleomammalian cortex, is a set of brain structures located on both sides of the thalamus, immediately beneath the medial temporal lobe of the cerebrum primarily in the forebrain. [1] Its various components support a variety of functions including emotion, behavior, long-term memory, and olfaction. [2]
Hippocampus and associated structures; Fornix and septal nuclei; Subcortical areas: Septal nuclei; Amygdala; Nucleus accumbens; Diencephalic structures: Hypothalamus; Mammillary bodies; Anterior nuclei of thalamus; Other areas that have been included in the limbic system include the: Stria medullaris; Central gray and dorsal and ventral nuclei ...
The importance of non-cholinergic neurons in the basal forebrain structures has been shown in working together with the cholinergic neurons in a dynamically modulatory way. This is seen to play a significant role in cognitive functions. [2] Nitric oxide production in the basal forebrain is both necessary and sufficient to produce sleep. [5]
In birds, there are also major changes in forebrain structure. [37] These distortions can make it difficult to match brain components from one species with those of another species. [38] Here is a list of some of the most important vertebrate brain components, along with a brief description of their functions as currently understood:
The diencephalon is the region of the embryonic vertebrate neural tube that gives rise to anterior forebrain structures including the thalamus, hypothalamus, posterior portion of the pituitary gland, and the pineal gland. The diencephalon encloses a cavity called the third ventricle.
The medial forebrain bundle may serve as a target in treating treatment-resistant depression. [8] Since the MFB connects areas of the brain which are involved with motivated behavior, mood regulation, and antidepressant response the stimulation of the MFB through deep brain stimulation could be an effective form of treatment.