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Discoid lupus erythematosus (DLE) is an uncommon autoimmune disease of the basal cell layer of the skin. It occurs in humans [1] and cats, more frequently occurring in dogs. It was first described in dogs by Griffin and colleagues in 1979. [2] [3] DLE is one form of cutaneous lupus erythematosus (CLE). DLE occurs in dogs in two forms: a ...
Bruch's membrane thickens with age, slowing the transport of metabolites. This may lead to the formation of drusen in age-related macular degeneration. [4] There is also a buildup of deposits (Basal Linear Deposits or BLinD and Basal Lamellar Deposits BLamD) on and within the membrane, primarily consisting of phospholipids.
Dog with bulging and clouded right eye. Glaucoma often goes unnoticed in dogs until it is in a more severe state. There are rarely any symptoms in the early stages of the disease so regular eye checks by qualified veterinary professionals are important. Dogs will sometimes rub the eye if it is painful.
Dog with atopic dermatitis, with signs around the eye created by rubbing. Atopy is a hereditary [3] and chronic (lifelong) allergic skin disease. Signs usually begin between 6 months and 3 years of age, with some breeds of dog, such as the golden retriever, showing signs at an earlier age. Dogs with atopic dermatitis are itchy, especially ...
Symptoms include eye redness, a yellow or greenish discharge, ulceration of the cornea, pigmented cornea, and blood vessels on the cornea. [ 63 ] Vogt–Koyanagi–Harada syndrome is a condition seen in dogs characterized by uveitis (inflammation of the inside of the eye), poliosis (whitening of hair), and vitiligo (loss of pigment in the skin).
Symptoms include sudden permanent blindness, but may occur more slowly over several days, weeks or months, [3] dilated pupils. Pupillary light reflexes are usually reduced but present; the slow phase mediated by melanopsin in retinal ganglion cells is retained.
Shock: Many of the symptoms seen in bloat (like restlessness and vomiting) are signs of shock, but dogs will also have pale gums and a rapid heart rate as the blood becomes trapped and they go ...
The terms “basal lamina” and “basement membrane” were often used interchangeably, until it was realised that all three layers seen with the electron microscope constituted the single layer seen with the light microscope. This has led to considerable terminological confusion; if used, the term “basal lamina” should be confined to its ...