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[67] [68] In 2016, the WHO published new guidelines for treatment, stating "There is an urgent need to update treatment recommendations for gonococcal infections to respond to changing antimicrobial resistance (AMR) patterns of N. gonorrhoeae. High-level resistance to previously recommended quinolones is widespread and decreased susceptibility ...
Since 2007, standard treatment has been third-generation cephalosporins, such as ceftriaxone, which are considered to be our "last line of defense". [80] [81] Recently, a high-level ceftriaxone-resistant strain of gonorrhea called H041 was discovered in Japan. Lab tests found it to be resistant to high concentrations of ceftriaxone, as well as ...
The antibiotic, which would be the first new gonorrhea treatment approved in decades, could make it to market by 2025. The World Health Organization estimates that globally there are more than 82 ...
Neisseria gonorrhoeae, the bacterium that causes the sexually transmitted infection gonorrhea, has developed antibiotic resistance to many antibiotics. The bacteria was first identified in 1879. [1] In the 1940s effective treatment with penicillin became available, but by the 1970s resistant strains predominated. Resistance to penicillin has ...
The first effective treatment for a sexually transmitted infection was salvarsan, a treatment for syphilis. With the discovery of antibiotics , a large number of sexually transmitted infections became easily curable, and this, combined with effective public health campaigns against STIs, led to a public perception during the 1960s and 1970s ...
Treatment typically consists of cephalosporin and fluoroquinolone antibiotics. [5] Gonococcemia is typically treated with intravenous or intramuscular cephalosporin antibiotics. [ 6 ] Approximately 10-30% of gonorrheal infections present with a co-infection of chlamydia , so it is common to add a one-time dose of oral azithromycin or ...