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The antibiotic, which would be the first new gonorrhea treatment approved in decades, could make it to market by 2025. The World Health Organization estimates that globally there are more than 82 ...
[67] [68] In 2016, the WHO published new guidelines for treatment, stating "There is an urgent need to update treatment recommendations for gonococcal infections to respond to changing antimicrobial resistance (AMR) patterns of N. gonorrhoeae. High-level resistance to previously recommended quinolones is widespread and decreased susceptibility ...
Neisseria gonorrhoeae, the bacterium that causes the sexually transmitted infection gonorrhea, has developed antibiotic resistance to many antibiotics. The bacteria was first identified in 1879. [1] In the 1940s effective treatment with penicillin became available, but by the 1970s resistant strains predominated. Resistance to penicillin has ...
Since 2007, standard treatment has been third-generation cephalosporins, such as ceftriaxone, which are considered to be our "last line of defense". [84] [85] Recently, a high-level ceftriaxone-resistant strain of gonorrhea called H041 was discovered in Japan. Lab tests found it to be resistant to high concentrations of ceftriaxone, as well as ...
Along with practicing safer sex, Hamill says patients should be aware of what the CDC’s screening guidelines are on who should get tested regularly for STIs, including gonorrhea — especially ...
Zoliflodacin (development codes AZD0914 and ETX0914) is an experimental antibiotic that is being studied for the treatment of infection with Neisseria gonorrhoeae (). [1] It has a novel mechanism of action which involves inhibition of bacterial type II topoisomerases. [2]