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  2. Hyperbilirubinemia in adults - Wikipedia

    en.wikipedia.org/wiki/Hyperbilirubinemia_in_adults

    Hyperbilirubinemia is a clinical condition describing an elevation of blood bilirubin level due to the inability to properly metabolise or excrete bilirubin, a product of erythrocytes breakdown. In severe cases, it is manifested as jaundice , the yellowing of tissues like skin and the sclera when excess bilirubin deposits in them. [ 1 ]

  3. Neonatal cholestasis - Wikipedia

    en.wikipedia.org/wiki/Neonatal_cholestasis

    Neonatal cholestasis refers to elevated levels of conjugated bilirubin identified in newborn infants within the first few months of life. [1] Conjugated hyperbilirubinemia is clinically defined as >20% of total serum bilirubin or conjugated bilirubin concentration greater than 1.0 mg/dL regardless of total serum bilirubin concentration. [2]

  4. Neonatal jaundice - Wikipedia

    en.wikipedia.org/wiki/Neonatal_jaundice

    Neonatal jaundice is a ... and since 2022 home phototherapy is recommended as an alternative to readmission to hospital in the American national guidelines. ...

  5. Jaundice - Wikipedia

    en.wikipedia.org/wiki/Jaundice

    Jaundice, also known as icterus, is a yellowish or greenish pigmentation of the skin and sclera due to high bilirubin levels. [3] [6] Jaundice in adults is typically a sign indicating the presence of underlying diseases involving abnormal heme metabolism, liver dysfunction, or biliary-tract obstruction. [7]

  6. Bili light - Wikipedia

    en.wikipedia.org/wiki/Bili_light

    Infant undergoing bili light therapy in a United States maternity ward. A bili light [1] [2] is a light therapy tool to treat newborn jaundice (hyperbilirubinemia).High levels of bilirubin can cause brain damage (kernicterus), leading to cerebral palsy, auditory neuropathy, gaze abnormalities and dental enamel hypoplasia.

  7. Hemolytic disease of the newborn (anti-Kell) - Wikipedia

    en.wikipedia.org/wiki/Hemolytic_disease_of_the...

    The hemolytic process can result in anemia, hyperbilirubinemia, neonatal thrombocytopenia, and neonatal neutropenia. [6] With the use of RhD Immunoprophylaxis, (commonly called Rhogam), the incidence of anti-D has decreased dramatically and other alloantibodies are now a major cause of HDN.

  8. Liver function tests - Wikipedia

    en.wikipedia.org/wiki/Liver_function_tests

    When total bilirubin levels exceed 40 μmol/L, bilirubin deposition at the sclera, skin, and mucous membranes will give these areas a yellow colour, thus it is called jaundice. [6] The increase in predominantly unconjugated bilirubin is due to overproduction, reduced hepatic uptake of the unconjugated bilirubin and reduced conjugation of bilirubin.

  9. Hereditary hyperbilirubinemia - Wikipedia

    en.wikipedia.org/wiki/Hereditary_hyperbilirubinemia

    There are additional rare causes of hereditary hyperbilirubinemia like Lucey-Driscoll syndrome and Heme Oxygenase-1 Deficiency. [1] Both Gilbert syndrome and Crigler-Najjar syndrome cause an elevated unconjugated bilirubin level due to mutations in the UGT1A1 gene, which conjugates bilirubin within liver cells so it can be excreted.