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Isosorbide dinitrate is in the nitrate family of medications and works by dilating blood vessels. [1] Isosorbide dinitrate was first written about in 1939. [3] It is on the World Health Organization's List of Essential Medicines. [4] Isosorbide dinitrate is available as a generic medication. [1] [5] A long-acting form exists. [1]
N-(1-Naphthyl)ethylenediamine dihydrochloride is widely used in the quantitative analysis of nitrate and nitrite in water samples by colorimetry.It readily undergoes a diazonium coupling reaction in the presence of nitrite to give a strongly colored azo compound.
Nitrates mainly differ in speed and duration of their action. Glyceryl trinitrate acts fast and short (10 to 30 minutes), while most other nitrates have a slower onset of action, but are effective for up to six hours. Molsidomine, as has been mentioned, not only acts slowly but also differs from the nitrates in exhibiting no tolerance. [2]
Erythritol tetranitrate (ETN) is an explosive compound chemically similar to PETN, [1] though it is thought to be slightly more sensitive to friction and impact.. Like many nitrate esters, ETN acts as a vasodilator, and was the active ingredient in the original "sustained release" tablets, made under a process patent in the early 1950s, called "nitroglyn".
The first long-acting (depot) injections were antipsychotics fluphenazine and haloperidol. [2] The concept of a depot injection arose before 1950, and originally was used to describe antibiotic injections that lasted longer to allow for less frequent administration.
The recommended maximum limits by the World Health Organization in drinking water are 3 mg L −1 and 50 mg L −1 for nitrite and nitrate ions, respectively. [16] Ingesting too much nitrite and/or nitrate through well water is suspected to cause methemoglobinemia. [17]
The compound is a salt with separated hydroxyammonium and nitrate ions. [2] Hydroxylammonium nitrate is unstable because it contains both a reducing agent (hydroxylammonium cation) and an oxidizer , [3] the situation being analogous to ammonium nitrate. It is usually handled as an aqueous solution with small amount of nitric acid as a stabilizer.
Evaporating the resulting solution yields hydrated neodymium(III) nitrate, where the hexahydrate form is the most common. Heating the hexahydrate further will obtain the anhydrous form. Reacting neodymium(III) chloride with sodium arsenate in solution would obtain neodymium(III) arsenate, [10] which is a faint pink powder that is insoluble in ...