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OCT can be used to capture functional images of blood flow, a technique known as optical coherence tomography angiography (OCT-A). SV-OCT is one method for OCT-A that uses the variance of consecutively acquired images to detect flow at the micron scale. SV-OCT can be used to measure the microvasculature of tissue.
[15] [16] [17] OCTA may make use of speckle variance optical coherence tomography. OCTA uses motion contrast between cross-sectional OCT scans (B-frames) to differentiate blood flow from static tissue, enabling imaging of vascular anatomy.
Optical coherence tomogram of a fingertip. It is possible to observe the sweat glands, having "corkscrew appearance" Interferometric reflectometry of biological tissue, especially of the human eye using short-coherence-length light (also referred to as partially-coherent, low-coherence, or broadband, broad-spectrum, or white light) was investigated in parallel by multiple groups worldwide ...
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Optical coherence tomography (OCT) is a technique that displays images of the tissue by using the backscattered light. [citation needed] Not only conserving the excellence of OCT, doppler optical coherence tomography also combines the doppler effect principle as a whole, which result in tomographic images with high resolution. [1]
The first intravascular in vivo use in a preclinical model was reported in 1994 [6] and first in human, clinical imaging in 2003. [7] The first OCT imaging catheter and system was commercialized by LightLab Imaging, Inc., a company based in Massachusetts formed following a technology transfer in 1997 from Fujimoto's lab (MIT). [8]
Spectroscopic optical coherence tomography (SOCT) is an optical imaging and sensing technique, which provides localized spectroscopic information of a sample based on the principles of optical coherence tomography (OCT) and low coherence interferometry. The general principles behind SOCT arise from the large optical bandwidths involved in OCT ...
[5] [6] Optical techniques have also been proposed for elastography to probe mechanical properties of tissues dates back to at least the 1950s. [7] In 1998, Schmitt first proposed optical coherence elastography (OCE), in employing optical coherence tomography (OCT) detect depth-resolved sample deformation induced by quasi-static compression. [8]