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  2. Atorvastatin - Wikipedia

    en.wikipedia.org/wiki/Atorvastatin

    Statins with shorter half-lives are more effective when taken in the evening, so their peak effect occurs when the body's natural cholesterol production is at its highest. A recent meta-analysis suggested that statins with longer half-lives, including atorvastatin, may also be more effective at lowering LDL cholesterol if taken in the evening. [40]

  3. Statin - Wikipedia

    en.wikipedia.org/wiki/Statin

    Media reporting on statins is often negative, and patient leaflets inform patients that rare but potentially serious muscle problems can occur during statin treatment. These create expectations of harm. Nocebo symptoms are real and bothersome and are a major barrier to treatment.

  4. Rosuvastatin - Wikipedia

    en.wikipedia.org/wiki/Rosuvastatin

    Serious side effects may include rhabdomyolysis, liver problems, and diabetes. [6] Use during pregnancy may harm the baby. [6] Like all statins, rosuvastatin works by inhibiting HMG-CoA reductase, an enzyme found in the liver that plays a role in producing cholesterol. [6]

  5. Statins are Effective Even for People Over Age 75, What ... - AOL

    www.aol.com/statins-effective-even-people-over...

    Statins appear to be effective at preventing cardiovascular disease and death in older adults, according to new research. Most clinical trials evaluating statins have not included people 75 and ...

  6. 17 million US adults may no longer receive statin therapy for ...

    www.aol.com/17-million-us-adults-may-160000273.html

    These guidelines recommend statin therapy for adults between forty and seventy-five who have diabetes, high cholesterol levels, or an estimated 10-year atherosclerotic cardiovascular disease risk ...

  7. Discovery and development of statins - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The statins differ with respect to their ring structure and substituents. These differences in structure affect the pharmacological properties of the statins, such as: [6] Affinity for the active site of the HMGR; Rates of entry into hepatic and non-hepatic tissues; Availability in the systemic circulation for uptake into non-hepatic tissues