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4879 18158 Ensembl ENSG00000120937 ENSMUSG00000029019 UniProt P16860 P40753 RefSeq (mRNA) NM_002521 NM_001287348 NM_008726 RefSeq (protein) NP_002512 NP_002512 NP_001274277 NP_032752 Location (UCSC) Chr 1: 11.86 – 11.86 Mb Chr 4: 148.07 – 148.07 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Brain natriuretic peptide (BNP), also known as B-type natriuretic peptide, is a hormone ...
There is no level of BNP that perfectly separates patients with and without heart failure. [14]In screening for congenital heart disease in pediatric patients, an NT-proBNP cut-off value of 91 pg/mL could differentiate an acyanotic heart disease (ACNHD) patient from a healthy patient with a sensitivity of 84% and specificity of 42%. [15]
BNP was first discovered in pig brain tissue but was later found more abundant in the heart (Mukoyama et al. 1991; Mukoyama et al. 1990). The human gene that encodes for BNP is called NPPB (GeneID 4879) and is located on chromosome 1 at 1p36.2. In mice, NPPb is found on chromosome 4. [3]
Reviewed by Dietitian Annie Nguyen, M.A., RD. Your heart is arguably the hardest-working muscle in your body. Every day it pumps nearly 2,000 gallons of blood through your arteries to supply the ...
Eating breakfast regularly has been shown to help reduce the risk of developing type 2 diabetes, cardiovascular disease and obesity, according to UC Davis Health. There is also evidence that ...
When eggs are paired with foods high in saturated fat like butter, bacon or sausage, it will likely increase LDL cholesterol, which can raise heart disease risk over time. On the other hand, pair ...
Brain natriuretic peptide 32 (BNP) is another biomarker commonly tested for heart failure. [74] [6] [75] An elevated NT-proBNP or BNP is a specific test indicative of heart failure. Additionally, NT-proBNP or BNP can be used to differentiate between causes of dyspnea due to heart failure from other causes of dyspnea.
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