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Alkalihalobacillus clausii (synonym Bacillus clausii) is a rod-shaped, motile, and spore-forming bacterium that lives in the soil but is also a natural microbiota of the mammalian gastrointestinal tract. It is classified as probiotic microorganism that maintains a symbiotic relationship with the host organism. [1]
Viable spores in food can become vegetative cells in the intestines and produce a range of diarrheal enterotoxins, so elimination of spores is desirable. In wet heat (poaching, simmering, boiling, braising, stewing, pot roasting, steaming), spores require more than 5 minutes at 121 °C (250 °F) at the coldest spot to be destroyed.
A specific microbial metabolite in the gut microbiome that helps regulate brain activity is linked to anxiety, a new study in mice has found, suggesting that acting on gut bacteria may help ...
It is also considered a probiotic. [4] It is a gram-positive rod that may appear long and filamentous. It is non-motile and does not form spores. It is also non-pathogenic. It is regarded as aciduric or acidophilic, since it requires a low pH (around 5.4–4.6) to grow effectively. In addition, it is anaerobic. [5]
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The safety of fecal microbiota spores (live) was evaluated in a randomized, double-blind, placebo-controlled clinical study and an open-label clinical study conducted in the US and Canada. [2] The participants who suffered from recurrent C. difficile infection were subjected to 48 to 96 hours post-antibacterial treatment and their symptoms were ...