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Itching is one of the most frequent adverse effects of opioid therapy. [4] A common artificial colloid used in clinical fluid management is hydroxyethyl starch (HES). Well-defined side effects, such as coagulopathy, clinical bleeding, anaphylactoid reactions, and pruritus, can make using HES more difficult. [5]
The following rare side effects are more serious. Like all statins, rosuvastatin can possibly cause myopathy, rhabdomyolysis: [14] [4] muscle pain, tenderness, or weakness; lack of energy; fever; chest pain; jaundice: yellowing of the skin or eyes; dark colored, or foamy urine; pain in the upper right part of the abdomen; nausea; extreme ...
Potentiates CNS sedatives, [3] chronic use might cause a reversible dry skin condition. [18] Khat: qat Catha edulis: Chronic liver dysfunction [3] [19] Kratom: Mitragyna speciosa: Hepatotoxicity [20] [19] Liquorice root Glycyrrhiza glabra: Hypokalemia, hypertension, arrhythmias, edema [5] Lobelia: asthma weed, pukeweed, vomit wort Lobelia inflata
According to very low certainty data, oral doxycycline may help with symptoms like itchiness, burning, or watery eyes, but may induce more side effects. [23] A review of treatments showed that the anti-mite drug ivermectin can be an effective treatment for reducing symptoms. [24]
Dizziness is often reported as being the withdrawal symptom that lasts the longest. A study testing neuropsychological factors found psychophysiological markers differing from normals, and concluded that protracted withdrawal syndrome was a genuine iatrogenic condition caused by the long-term use. [ 126 ]
Side effects include burning sensation (common), [4] redness, discharge, watery eyes, eye pain, foreign body sensation, itching, stinging, and blurred vision. [14] [4] Long term use of ciclosporin at high doses is associated with an increased risk of cancer. [48] [49] Cheaper generic alternatives are available in some countries. [50]
Mast cell intermediaries cause an allergic inflammation and symptoms through the activation of inflammatory cells. [3] When histamine is released from mast cells, it binds to H1 receptors on nerve endings and causes the ocular symptom of itching. Histamine also binds to H1 and H2 receptors of the conjunctival vasculature and causes vasodilatation.
It causes mucous membranes in the nose, eyes and throat to become inflamed and itchy as they work to eject the allergen. [10] Diagnosis is typically based on a combination of symptoms and a skin prick test or blood tests for allergen-specific IgE antibodies. [4] These tests, however, can give false positives. [4]