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Similar mechanisms have been shown to control crest movement in the hindbrain within rhombomeres 4, 5, and 7, which distribute crest cells to brachial arches 2, 3, and 4 respectively. In C. elegans a knockout of the vab-1 gene, known to encode an Eph receptor, and its Ephrin ligand vab-2 results in two cell migratory processes being affected ...
Ethylphenidate (EPH) is a central nervous system (CNS) stimulant and a close analog of methylphenidate.. Ethylphenidate acts as a norepinephrine–dopamine reuptake inhibitor, meaning it effectively boosts the levels of the norepinephrine and dopamine neurotransmitters in the brain, by binding to, and partially blocking the transporter proteins that normally remove those monoamines from the ...
Ephrin ligands are divided into two subclasses of ephrin-A and ephrin-B based on their structure and linkage to the cell membrane. Ephrin-As are anchored to the membrane by a glycosylphosphatidylinositol (GPI) linkage and lack a cytoplasmic domain, while ephrin-Bs are attached to the membrane by a single transmembrane domain that contains a short cytoplasmic PDZ-binding motif.
In cell biology, there are a multitude of signalling pathways. Cell signalling is part of the molecular biology system that controls and coordinates the actions of cells.. Akt/PKB signalling pathway
The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family ...
EPH receptor A1 (ephrin type-A receptor 1) is a protein that in humans is encoded by the EPHA1 gene. [5] [6] This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system.
1948 13642 Ensembl ENSG00000125266 ENSMUSG00000001300 UniProt P52799 P52800 RefSeq (mRNA) NM_004093 NM_001372056 NM_001372057 NM_001372058 NM_010111 NM_001368299 RefSeq (protein) NP_004084 NP_001358985 NP_001358986 NP_001358987 NP_034241 NP_001355228 Location (UCSC) Chr 13: 106.49 – 106.54 Mb Chr 8: 8.67 – 8.71 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Ephrin-B2 is a ...
Ephrin type-B receptor 6 is a protein that in humans is encoded by the EPHB6 gene. [5]Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system.