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Adherens junctions uniquely disassemble in uterine epithelial cells to allow the blastocyst to penetrate between epithelial cells. [3] A similar cell junction in non-epithelial, non-endothelial cells is the fascia adherens. It is structurally the same, but appears in ribbonlike patterns that do not completely encircle the cells.
L1-Cell Adhesion Molecule (L1CAM) was first discovered to be important in neuron-related tissue development in the mid-1980s, and is a trans-membranal glycoprotein of approximately 200-220 kDa. On its extracellular domain, the L1CAM protein includes IgG -like and fibronectin -III (FN-III) repeats which allow for interaction with integrins and ...
The band-type of adherens junctions is associated with bundles of actin filaments that also encircle the cell just below the plasma membrane. Spot-like adherens junctions called focal adhesions help cells adhere to extracellular matrix. The cytoskeletal actin filaments that tie into adherens junctions are contractile proteins and in addition to ...
Schematic of cell adhesion. Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process can occur either through direct contact between cell surfaces such as cell junctions or indirect interaction, where cells attach to surrounding extracellular matrix, a gel-like structure containing molecules released ...
Adjacent epithelial cells are connected by adherens junctions on their lateral membranes. They are located just below tight junctions. Their function is to give shape and tension to cells and tissues and they are also the site of cell-cell signaling. Adherens junctions are made of cell adhesion molecules from the cadherin family. There are over ...
Using an electrical nerve impulse from a neuron of a neuromuscular junction to stimulate a muscle to contract is an example of very small [26] (about 0.05μm) vesicles being directly involved in regulating intercellular communication. The neuron produces thousands of tiny vesicles, each containing thousands of signalling molecules.
As synapses mature in the CA3 region, nectins and cadherins, which affiliate closely with one another in synaptic stabilization, are shifted to the periphery of the active zone and form the puncta adherens junction (PAJ). The PAJ functions much like the adherens junctions in epithelial tissues. The displacement of these CAMs and the formation ...
Smooth muscle differs from skeletal muscle and cardiac muscle in terms of structure, function, regulation of contraction, and excitation-contraction coupling. However, smooth muscle tissue tends to demonstrate greater elasticity and function within a larger length-tension curve than striated muscle. This ability to stretch and still maintain ...