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A mitochondrion (pl. mitochondria) is an organelle found in the cells of most eukaryotes, such as animals, plants and fungi. Mitochondria have a double membrane structure and use aerobic respiration to generate adenosine triphosphate (ATP), which is used throughout the cell as a source of chemical energy . [ 2 ]
The mitochondria contains its own set of DNA used to produce proteins found in the electron transport chain. The mitochondrial DNA only codes for about thirteen proteins that are used in processing mitochondrial transcripts, ribosomal proteins , ribosomal RNA , transfer RNA , and protein subunits found in the protein complexes of the electron ...
In cell biology, an organelle is a specialized subunit, usually within a cell, that has a specific function. The name organelle comes from the idea that these structures are parts of cells, as organs are to the body , hence organelle, the suffix -elle being a diminutive .
In terms of protein synthesis, the necessary organelles are relatively near one another. The nucleolus within the nuclear envelope is the location of ribosome synthesis. The destination of synthesized ribosomes for protein translation is rough endoplasmic reticulum (rough ER), which is connected to and shares the same membrane with the nucleus.
This ratio is variable and mitochondria from cells that have a greater demand for ATP, such as muscle cells, contain even more cristae. Cristae membranes are studded on the matrix side with small round protein complexes known as F 1 particles, the site of proton-gradient driven ATP synthesis. Cristae affect overall chemiosmotic function of ...
Each mitochondrion has several copies of the mtDNA molecule and the number of mtDNA molecules is a limiting factor in mitochondrial fission. After the mitochondrion has enough mtDNA, membrane area, and membrane proteins, it can undergo fission (very similar to that which bacteria use) to become two mitochondria.
Mitochondria are dynamic organelles with the ability to fuse and divide , forming constantly changing tubular networks in most eukaryotic cells. These mitochondrial dynamics, first observed over a hundred years ago [ 1 ] are important for the health of the cell, and defects in dynamics lead to genetic disorders .
Simplified structure of a mitochondrion. The intermembrane space (IMS) is the space occurring between or involving two or more membranes. [1] In cell biology, it is most commonly described as the region between the inner membrane and the outer membrane of a mitochondrion or a chloroplast.