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[4] [5] The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, as in asparagine and glutamine. It can be viewed as a derivative of a carboxylic acid ( R−C(=O)−OH ) with the hydroxyl group ( −OH ) replaced by an amino group ( −NR′R″ ); or ...
The amide bond is synthesized when the carboxyl group of one amino acid molecule reacts with the amino group of the other amino acid molecule, causing the release of a molecule of water (H 2 O), hence the process is a dehydration synthesis reaction. The dehydration condensation of two amino acids to form a peptide bond (red) with expulsion of ...
Structures of three kinds of amides: an organic amide (carboxamide), a sulfonamide, and a phosphoramide. In chemistry, the term amide (/ ˈ æ m aɪ d / or / ˈ æ m ɪ d / or / ˈ eɪ m aɪ d /) [1] [2] [3] is a compound with the functional group R n E(=O) x NR 2, where x is not zero, E is some element, and each R represents an organic group or hydrogen. [4]
Deamidation reaction of Asn-Gly (top right) to Asp-Gly (at left) or iso(Asp)-Gly (in green at bottom right) Deamidation is a chemical reaction in which an amide functional group in the side chain of the amino acids asparagine or glutamine is removed or converted to another functional group.
In organic chemistry, peptide synthesis is the production of peptides, compounds where multiple amino acids are linked via amide bonds, also known as peptide bonds. Peptides are chemically synthesized by the condensation reaction of the carboxyl group of one amino acid to the amino group of another.
Isopeptide bonds lead to branching in the primary sequence of a protein. Proteins formed from normal peptide bonds typically have a linear primary sequence. Amide bonds, and thus isopeptide bonds, are stabilized by resonance (electron delocalization) between the carbonyl oxygen, the carbonyl carbon, and the nitrogen atom. The bond strength of ...
Plant-based protein powders—made from rice, peas or soy—were found to contain triple the amount of lead compared to whey protein powders, which are made from the liquid byproduct of cheese ...
N-Acetylglucosamine molecule. N-Acetylglucosamine (GlcNAc) is an amide derivative of the monosaccharide glucose.It is a secondary amide between glucosamine and acetic acid.It is significant in several biological systems.