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Promethazine, sold under the brand name Phenergan among others, is a first-generation antihistamine, sedative, and antiemetic used to treat allergies, insomnia, and nausea. It may also help with some symptoms associated with the common cold [ 4 ] and may also be used for sedating people who are agitated or anxious, an effect that has led to ...
In July 1975, the J. B. Williams Co. began marketing Sominex 2. [37] On November 24, 1975, Attorney General Evelle J. Younger filed suit on behalf of the State of California against Williams Co., stating that the product did not warn against use by pregnant or nursing women or persons with asthma or COPD, nor did it notify consumers that it should not be used in conjunction with alcohol. [38]
Consumer Reports is a United States-based non-profit organization which conducts product testing and product research to collect information to share with consumers so that they can make more informed purchase decisions in any marketplace.
The most common antihistamines utilized for this purpose include hydroxyzine, promethazine (enzyme induction especially helps with codeine and similar prodrug opioids), phenyltoloxamine, orphenadrine, and tripelennamine; some may also have intrinsic analgesic properties of their own, orphenadrine being an example.
Propiomazine, also known as 10-(2-dimethylaminopropyl)-2-propionylphenothiazine or as propionylpromethazine, is a phenothiazine derivative [4] and is structurally related to promethazine. The compound is provided medically as the hydrochloride and maleate salts. [6] [4] [7]
Doses of hydroxyzine hydrochloride used for sleep range from 25 to 100 mg. [15] [16] [17] As with other antihistamine sleep aids, hydroxyzine is usually only prescribed for short term or "as-needed" use since tolerance to the CNS (central nervous system) effects of hydroxyzine can develop in as little as a few days.
It was formerly sold over-the-counter in the United States under the trade name Ulo, as a syrup with a dosage of 25 mg/5 mL. [6] It is now marketed under the brand name of Ninjacof and others in the U.S. It is marketed in Canada under the trade name Ulone. GM Pharmaceuticals owns the patents to 113 combinations with Chlophedianol and was the ...
A 2004 Journal of the Medical Library Association review noted that "approximately half of the [laboratory test results] reports indicate the date the review was posted". [17] For a fee, ConsumerLab.com offers a voluntary certification program. Products that pass the certification can use the "CL Seal of Approval" for which there is a licensing ...