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The trihydroxybenzenes (or benzenetriols) are organic compounds with the formula C 6 H 3 (OH) 3. Also classified as polyphenols, they feature three hydroxyl groups substituted onto a benzene ring. They are white solids with modest solubility in water. [1]
The LD50 (oral, rats) is 756 mg/kg. Animal studies have shown that 1,2,4-trichlorobenzene affects the liver and kidney, and is possibly a teratogen. [4] There is no regulated occupational exposure limit for chemical exposure, but the National Institute for Occupational Safety and Health recommends no greater exposure than 5 ppm, over an 8-hour workday.
Thus, the two substrates of this enzyme are 1,2,3,5-tetrahydroxybenzene and 1,2,3-trihydroxybenzene (pyrogallol), whereas its two products are 1,3,5-trihydroxybenzene (phloroglucinol) and 1,2,3,5-tetrahydroxybenzene. This enzyme participates in benzoic acid degradation via CoA ligation.
Trichlorobenzene (TCB) may refer to any of three isomeric chlorinated derivatives of benzene with the molecular formula C 6 H 3 Cl 3. They differ by the positions of the chlorine atoms around the ring: 1,2,3-Trichlorobenzene; 1,2,4-Trichlorobenzene; 1,3,5-Trichlorobenzene
The 3 substrates of this enzyme are 2-hydroxy-1,4-benzoquinone, NADH, and H +, whereas its two products are 1,2,4-trihydroxybenzene and NAD +. This enzyme participates in gamma-hexachlorocyclohexane degradation and 1,4-dichlorobenzene degradation .
This category has the following 4 subcategories, out of 4 total. H. Hydroxyquinols (1 C, 9 P) P. Phloroglucinols (1 C, 10 P) Pyrogallols (2 C, 38 P) T ...
These substrates include monochlorophenols, dichlorophenols, and more complex species such as the pesticide 2,4,5-T. [5] Hydroxyquinol commonly occurs in nature as a biodegradation product of catechin , a natural phenol found in plants (e.g. by soil bacteria Bradyrhizobium japonicum ). [ 6 ]
It is a metabolite in the degradation of 3,4,5-trihydroxybenzoate (gallic acid) by Eubacterium oxidoreducens. [ 1 ] The enzyme pyrogallol hydroxytransferase uses 1,2,3,5-tetrahydroxybenzene and 1,2,3-trihydroxybenzene ( pyrogallol ), whereas its two products are 1,3,5-trihydroxybenzene ( phloroglucinol ) and 1,2,3,5-tetrahydroxybenzene.