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Peptic ulcer disease is when the inner part of the stomach's gastric mucosa (lining of the stomach), the first part of the small intestine, or sometimes the lower esophagus, gets damaged. An ulcer in the stomach is called a gastric ulcer , while one in the first part of the intestines is a duodenal ulcer . [ 1 ]
Endoscopic image of peptic stricture, or narrowing of the esophagus near the junction with the stomach: This is a complication of chronic gastroesophageal reflux disease and can be a cause of dysphagia or difficulty swallowing. The diagnosis of GERD is usually made when typical symptoms are present. [42]
Acid peptic diseases, such as peptic ulcers, Zollinger-Ellison syndrome, and gastroesophageal reflux disease, are caused by distinct but overlapping pathogenic mechanisms involving acid effects on mucosal defense. Acid reflux damages the esophageal mucosa and may also cause laryngeal tissue injury, leading to the development of pulmonary ...
For example, in about 10% of the American public, gastric or peptic ulcers can become a problem. Ulcers are sores that form in soft tissue, such as the lining of the digestive tract, and gastric ...
What Causes Stomach Ulcers? “A peptic ulcer is a sore or a break in the tissue that lines your stomach or small intestine,” explains Dr. Leah DeCoste, MD, a gastroenterologist with Gastro ...
Peptic ulcer disease, a wearing away of the stomach lining, can be asymptomatic in some cases, but others are severe enough to make a patient double over in pain, two doctors said.
F. Reigel suggests that ulcers are caused by excess acid. [1] Bacillus coli (E. coli) 1906 Krienitz finds bacteria in the stomach of people with gastric cancer. [2] Turck feeds dogs Bacillus coli and produces ulcers. [7] 1907 Berkley Moynihan suggests that acid is a cause of ulcers. [1] 1910
This is an accepted version of this page This is the latest accepted revision, reviewed on 7 January 2025. Circumstances, mechanisms, and factors of tobacco consumption on human health "Health effects of smoking" and "Dangers of smoking" redirect here. For cannabis, see Effects of cannabis. For smoking crack cocaine, see Crack cocaine § Health issues. "Smoking and health" redirects here. For ...