Search results
Results From The WOW.Com Content Network
On the other hand, the program XNU is used to mask off the tandem repeats in protein sequences. Make a k-letter word list of the query sequence. Take k=3 for example, we list the words of length 3 in the query protein sequence (k is usually 11 for a DNA sequence) "sequentially", until the last letter of the query sequence is included. The ...
The one-hybrid variation of this technique is designed to investigate protein–DNA interactions and uses a single fusion protein in which the AD is linked directly to the binding domain. The binding domain in this case however is not necessarily of fixed sequence as in two-hybrid protein–protein analysis but may be constituted by a library.
The genetic instructions of every replicating cell in a living organism are contained within its DNA. [2] Throughout the cell's lifetime, this information is transcribed and replicated by cellular mechanisms to produce proteins or to provide instructions for daughter cells during cell division, and the possibility exists that the DNA may be altered during these processes.
A BLAST variant called MegaBLAST indexes 4 databases to speed up alignments. [9] BLAT can extend on multiple perfect and near-perfect matches (default is 2 perfect matches of length 11 for nucleotide searches and 3 perfect matches of length 4 for protein searches), while BLAST extends only when one or two matches occur close together. [1] [9]
Protein A, B and C are isoforms encoded from the same gene through alternative splicing. A protein isoform, or "protein variant", [1] is a member of a set of highly similar proteins that originate from a single gene and are the result of genetic differences. [2] While many perform the same or similar biological roles, some isoforms have unique ...
The deduced amino acid sequence can be saved in various formats and searched against the sequence database using the basic local alignment search tool (BLAST) server. The ORF Finder should be helpful in preparing complete and accurate sequence submissions. It is also packaged with the Sequin sequence submission software (sequence analyser).
Alternative splicing produces three protein isoforms.Protein A includes all of the exons, whereas Proteins B and C result from exon skipping.. Alternative splicing, or alternative RNA splicing, or differential splicing, is an alternative splicing process during gene expression that allows a single gene to produce different splice variants.
The protein encoded by the gene goes by the same name, Armadillo like containing helical domain 1. The isoelectric point of the ARMH1 protein is around a pH of 5.5. [16] The protein has 2 known major domains, one being a transmembrane domain and the other being a coiled coil. [17] Within the coiled coil domains, the ARMH1 protein has 24 alpha ...