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Ascites (/ ə ˈ s aɪ t i z /; [5] Greek: ἀσκός, romanized: askos, meaning "bag" or "sac" [6]) is the abnormal build-up of fluid in the abdomen. [1] Technically, it is more than 25 ml of fluid in the peritoneal cavity, although volumes greater than one liter may occur. [4]
If a heart failure patient exhibits a resistance to or poor response to diuretic therapy, ultrafiltration or aquapheresis may be needed to achieve adequate control of fluid retention and congestion. The use of such mechanical methods of fluid removal can produce meaningful clinical benefits in patients with diuretic-resistant heart failure and ...
Chronic kidney disease causes excess fluid retention that is often treated with diet adjustments and diuretics. [2] Metolazone may be combined with other diuretics (typically loop diuretics) to treat diuretic resistance in congestive heart failure , chronic kidney disease, and nephrotic syndrome. [ 3 ]
It is recommended that patients on fluid restriction maintain a log to track daily fluid intake. [3] Symptoms of fluid build up due to underlying heart issues include, increased blood pressure, difficulty breathing, shortness of breath, bloating, swelling and nausea. [4] Patients with terminal illness may refuse both nutrition and hydration. [5]
Abdominal distension occurs when substances, such as air (gas) or fluid, accumulate in the abdomen causing its expansion. [1] It is typically a symptom of an underlying disease or dysfunction in the body, rather than an illness in its own right. People with this condition often describe it as "feeling bloated".
This will promote sodium reabsorption and fluid retention, causing diuretic resistance. Other factors includes gut edema which slows down the absorption of oral loop diuretics. Chronic kidney disease (CKD) reduces renal flow rate, reducing the delivery of diuretic molecules into the nephron, limiting sodium excretion and increasing sodium ...
Abdominal compartment syndrome is defined as an intra-abdominal pressure above 20 mmHg with evidence of organ failure. Abdominal compartment syndrome develops when the intra-abdominal pressure rapidly reaches certain pathological values, within several hours (intra-abdominal hypertension is observed), and lasts for 6 or more hours.
Fluid from the body enters the intestinal lumen during digestion. This fluid is isosmotic with the blood and contains a high quantity, about 142 mEq/L, of sodium. A healthy individual secretes 2000–3000 milligrams of sodium per day into the intestinal lumen. Nearly all of this is reabsorbed so that sodium levels in the body remain constant ...