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Dose and dose rate are used to measure different quantities [1] in the same way that distance and speed are used to measure different quantities. When considering stochastic radiation effects, only the total dose is relevant; each incremental unit of dose increases the probability that the stochastic effect happens. [ 4 ]
Committed equivalent dose, H T (t) is the time integral of the equivalent dose rate in a particular tissue or organ that will be received by an individual following intake of radioactive material into the body by a Reference Person, where s is the integration time in years. [13]
Count rate does not universally equate to dose rate, and there is no simple universal conversion factor. Any conversions are instrument-specific. Counts is the number of events detected, but dose rate relates to the amount of ionising energy deposited in the sensor of the radiation detector. The conversion calculation is dependent on the ...
In pharmacokinetics, a maintenance dose is the maintenance rate [mg/h] of drug administration equal to the rate of elimination at steady state. This is not to be confused with dose regimen , which is a type of drug therapy in which the dose [mg] of a drug is given at a regular dosing interval on a repetitive basis.
In pharmacokinetics, the rate of infusion (or dosing rate) refers not just to the rate at which a drug is administered, but the desired rate at which a drug should be administered to achieve a steady state of a fixed dose which has been demonstrated to be therapeutically effective. Abbreviations include K in, [1] K 0, [2] or R 0.
Absorbed dose is a dose quantity which is the measure of the energy deposited in matter by ionizing radiation per unit mass. Absorbed dose is used in the calculation of dose uptake in living tissue in both radiation protection (reduction of harmful effects), and radiology (potential beneficial effects, for example in cancer treatment).
The International Committee for Weights and Measures states: "In order to avoid any risk of confusion between the absorbed dose D and the dose equivalent H, the special names for the respective units should be used, that is, the name gray should be used instead of joules per kilogram for the unit of absorbed dose D and the name sievert instead ...
For such purposes, doses should be evaluated in terms of absorbed dose (in gray, Gy), and where high-LET radiations (e.g., neutrons or alpha particles) are involved, an absorbed dose, weighted with an appropriate RBE, should be used" Radiation weighting factors are largely based on the RBE of radiation for stochastic health risks. However, for ...