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Zolpidem tartrate, a common but potent sedative–hypnotic drug.Used for severe insomnia. Hypnotic (from Greek Hypnos, sleep [1]), or soporific drugs, commonly known as sleeping pills, are a class of (and umbrella term for) psychoactive drugs whose primary function is to induce sleep [2] (or surgical anesthesia [note 1]) and to treat insomnia (sleeplessness).
Sedatives and hypnotics should be avoided in people with dementia, [24] according to the medication appropriateness tool for co‐morbid health conditions in dementia criteria. [25] The use of these medications can further impede cognitive function for people with dementia, who are also more sensitive to side effects of medications. [citation ...
Chemical structure of the prototypical Z-drug zolpidem. Nonbenzodiazepines (/ ˌ n ɒ n ˌ b ɛ n z oʊ d aɪ ˈ æ z ɪ p iː n,-ˈ eɪ-/ [1] [2]), sometimes referred to colloquially as Z-drugs (as many of their names begin with the letter "z"), are a class of psychoactive, depressant, sedative, hypnotic, anxiolytic drugs that are benzodiazepine-like in uses, such as for treating insomnia [3 ...
The inhibitory effect of the available GABA is potentiated, leading to sedative and anxiolytic effects. For instance, those ligands with high activity at the α 1 are associated with stronger hypnotic effects, whereas those with higher affinity for GABA A receptors containing α 2 and/or α 3 subunits have good anti-anxiety activity. [178]
The long-term effects of benzodiazepines are very similar to the long-term effects of alcohol consumption (apart from organ toxicity) and other sedative-hypnotics. Withdrawal effects and dependence are not identical. Dependence can be managed, with a medical professional of course, but withdrawal can be fatal.
Somnifacient (from Latin somnus, sleep [1]), also known as sedatives or sleeping pills, is a class of medications that induces sleep. It is mainly used for treatment of insomnia . Examples of somnifacients include benzodiazepines , barbiturates and antihistamines .
Long-term use of sedative-hypnotics for insomnia lacks an evidence base and has traditionally been discouraged for reasons that include concerns about such potential adverse drug effects as cognitive impairment, anterograde amnesia, daytime sedation, motor incoordination, and increased risk of motor vehicle accidents and falls. [21]
Long-term use of sedative/hypnotics for insomnia lacks an evidence base and has traditionally been discouraged for reasons that include concerns about such potential adverse drug effects as cognitive impairment (anterograde amnesia), daytime sedation, motor incoordination, and increased risk of motor vehicle accidents and falls. In addition ...