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The antidote to atropine is physostigmine or pilocarpine. [medical citation needed] A common mnemonic used to describe the physiologic manifestations of atropine overdose is: "hot as a hare, blind as a bat, dry as a bone, red as a beet, and mad as a hatter". [33]
Physostigmine is the antidote of choice for Datura stramonium poisoning. It is also an antidote for Atropa belladonna poisoning, the same as for atropine. [3] It has also been used as an antidote for poisoning with GHB, [4] but is poorly effective and often causes additional toxicity, so is not a recommended treatment. [5]
Tricyclic antidepressant overdose is poisoning caused by excessive medication of the tricyclic antidepressant (TCA) type. Symptoms may include elevated body temperature , blurred vision, dilated pupils , sleepiness, confusion, seizures , rapid heart rate , and cardiac arrest . [ 1 ]
Benzodiazepine overdose ... Supportive care is the mainstay of treatment of benzodiazepine overdose. There is an antidote, ... Bradycardia is treated with atropine or ...
An antidote is a substance that can counteract a form of poisoning. [1] ... When given with Atropine: Organophosphate ... Warfarin overdose and some (but not all) ...
[35] [36] Atropine is a muscarinic antagonist, and thus blocks the action of acetylcholine peripherally. [37] These antidotes are effective at preventing lethality from OP poisoning, but current treatment lack the ability to prevent post-exposure incapacitation, performance deficits, or permanent brain damage. [38]
This process is known as aging. Aged phosphate-acetylcholinesterase conjugate is resistant to antidotes such as pralidoxime. Pralidoxime is often used with atropine (a muscarinic antagonist) to help reduce the parasympathetic effects of organophosphate poisoning. Pralidoxime is only effective in organophosphate toxicity.
This crisis may be masked by the concomitant use of atropine along with cholinesterase inhibitor medication in order to prevent side effects. Flaccid paralysis resulting from cholinergic crisis can be distinguished from myasthenia gravis by the use of the drug edrophonium (Tensilon), as it only worsens the paralysis caused by cholinergic crisis ...