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The concern goes beyond ineffectiveness; phenylephrine can come with side effects such as headaches, insomnia and nervousness. ... It also found people prefer oral decongestants over nasal spray 3 ...
The FDA is not questioning the effectiveness of nasal spray phenylephrine. Parikh said that it may improve symptoms temporarily , but she advised that people use nasal spray phenylephrine only for ...
Phenylephrine is also still thought to be effective when used as a nasal spray, said Dr. Wynne Armand, a primary care physician at Massachusetts General Hospital.
Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
Pseudoephedrine acts indirectly on the adrenergic receptor system, whereas phenylephrine and oxymetazoline are direct agonists. The effects are not limited to the nose, and these medicines may cause hypertension (high blood pressure) through vasoconstriction; it is for this reason that people with hypertension are advised to avoid them. Most ...
Rhinitis medicamentosa (or RM, also known as rebound congestion) is a condition of rebound nasal congestion suspected to be brought on by extended use of topical decongestants (e.g., oxymetazoline, phenylephrine, xylometazoline, and naphazoline nasal sprays) and certain oral medications (e.g., sympathomimetic amines and various 2-imidazolines) that constrict blood vessels in the lining of the ...