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Periods when gout symptoms are more severe are called gout flares or gout attacks. A gout flare comes on suddenly, and symptoms are often intense. ... If you have untreated gout for a long time ...
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Gout (/ ɡ aʊ t / GOWT [7]) is a form of inflammatory arthritis characterized by recurrent attacks of pain in a red, tender, hot, and swollen joint, [2] [8] caused by the deposition of needle-like crystals of uric acid known as monosodium urate crystals. [9] Pain typically comes on rapidly, reaching maximal intensity in less than 12 hours. [5]
Gout often affects the knee or big toe, but can attack any joint. ... Rather than a sudden occurrence in the big toe, gout may affect women slowly over time in several joints like the knees ...
[63] [64] At this time oral colchicine was being used to treat gout attacks. The only placebo control trial conducted using colchicine for acute gout attacks instructed physicians to give colchicine until pain relief or toxicity. [65] All patients on the colchicine arm had adverse events.
Febuxostat, sold under the brand name Uloric among others, is a medication used long-term to treat gout due to high uric acid levels. [7] It is generally recommended only for people who cannot take allopurinol. [8] [9] It is taken by mouth. [7] Common side effects include liver problems, nausea, joint pain, and a rash. [7]