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  2. Lidocaine - Wikipedia

    en.wikipedia.org/wiki/Lidocaine

    A 2021 study found that lidocaine 5% spray on glans penis 10-20 minutes prior to sexual intercourse significantly improves premature ejaculation. [28] Another study found that lidocaine-prilocaine cream 5% is effective in premature ejaculation and 20 minutes of application time before sexual intercourse.

  3. Topical anesthetic - Wikipedia

    en.wikipedia.org/wiki/Topical_anesthetic

    A topical anesthetic is a local anesthetic that is used to numb the surface of a body part. They can be used to numb any area of the skin as well as the front of the eyeball, the inside of the nose, ear or throat, the anus and the genital area. [1]

  4. Lidocaine/prilocaine - Wikipedia

    en.wikipedia.org/wiki/Lidocaine/prilocaine

    A 5% emulsion preparation, containing 2.5% each of lidocaine/prilocaine, is marketed by APP Pharmaceuticals under the trade name EMLA (an abbreviation for Eutectic Mixture of Local Anesthetics). [5] As a spray, it is marketed under the name Tempe (topical eutectic-like mixture for premature ejaculation) (PSD502) that can be used by men to help ...

  5. Prilocaine - Wikipedia

    en.wikipedia.org/wiki/Prilocaine

    It is used as a eutectic mixture with lidocaine, 50% w/w, as lidocaine/prilocaine. The mixture is an oil with a melting point of 18 °C (64 °F). A 5% emulsion preparation, containing 2.5% each of lidocaine/prilocaine, is marketed by APP Pharmaceuticals under the trade name EMLA (an abbreviation for eutectic mixture of local anesthetics). [3]

  6. Topical gels - Wikipedia

    en.wikipedia.org/wiki/Topical_gels

    Some additives and gelators added into the formulation may cause irritation problems, [5] [8] such as skin irritation, dermatitis or allergic conditions. [2] The increased water content in gels increases the chances of microbial or fungal attack, [5] [8] which may contaminate the gel, making it unsuitable for use. Considering the direct route ...

  7. Local anesthetic - Wikipedia

    en.wikipedia.org/wiki/Local_anesthetic

    Many local anesthetics fall into two general chemical classes, amino esters (top) and amino amides (bottom). A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, [1] providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes ...