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Ziconotide. Ziconotide, sold under the brand name Prialt, also called intrathecal ziconotide (ITZ) because of its administration route, is an atypical analgesic agent for the amelioration of severe and chronic pain. Derived from Conus magus, a cone snail, it is the synthetic form of an ω- conotoxin peptide. [2]
Venoms in medicine. Venom in medicine is the medicinal use of venoms for therapeutic benefit in treating diseases. Venom is any poisonous compound secreted by an animal intended to harm or disable another. When an organism produces a venom, its final form may contain hundreds of different bioactive elements that interact with each other ...
Cone snail species have shells that are roughly conical in shape. Many species have colorful patterning on the shell surface. [3] Cone snails are almost exclusively tropical in distribution. All cone snails are venomous and capable of stinging. Cone snails use a modified radula tooth and a venom gland to attack and paralyze their prey
structure summary. A conotoxin is one of a group of neurotoxic peptides isolated from the venom of the marine cone snail, genus Conus. Conotoxins, which are peptides consisting of 10 to 30 amino acid residues, typically have one or more disulfide bonds. Conotoxins have a variety of mechanisms of actions, most of which have not been determined.
Conus victoriae, common name the Queen Victoria cone, is a species of sea snail, a marine gastropod mollusk in the family Conidae, the cone snails and their allies. [1] Like all species within the genus Conus, these snails are predatory and venomous. They are capable of "stinging" humans, therefore live ones should be handled carefully or not ...
Biochemist. Awards. National Scientist of the Philippines. Lourdes J. Cruz (born May 19, 1942) is a Filipino biochemist whose research has contributed to the understanding of the biochemistry of toxic peptides from the venom of fish-hunting Conus marine snails. [1] Throughout the Philippines, she is known as the Sea Snail Venom Specialist.[2]